Extracture ni iki?
Ivyo bihimba vy’umubiri biva mu biti vy’ibiti vy’imiberoshi vyibanze cane biva ku rezitiro y’ibiti vy’i Boswellia, ahanini birimwo triterperoïdes z’umubiri zidasanzwe. Gukoresha ubuhinga bwo gukura CO₂ superpotlique superpolpountrique, burazigama ibintu vy’agaciro birwanya - umururumba kugira ngo umuntu aronke umuti usanzwe. Uwo muti wa kera uzwi ko ari "inzahabu y'amazi" ubu irasubira kugaragara mu gutegura ubuhinga.
Ivy'ingenzi n'ubuhinga
Acides z'i Boswell
Mu buryo bwihariye ibuza 5-lipoxygenase (5-LOX)
Ivyuma vy’ivyuma vy’ivyuma vy’ivyuma (85-90% vy’uguhagarika)
Guhitamwo MMP-3/9 mestloproteines
AKBA (Acetyl-11-keto- -asidellic)
Ivyinshi mu bihimba vy'umubiri bikomeye ({0}} igice c'umururumba (3-5x gikomeye)
Indirimbo ya NF{0}} Inzira y'inzira
Ivyiyumviro vy'agahahazo COX-2
Imigera
Ukwiyongera kw'ugukwiragira kw'imitsi y'umubiri (30-40%)
Ivyemezo vy'ubuhinga bwa kolajeni
Ihindura uburinganire bw'ubudahangarwa bw'umubiri
Inyungu z'Ivyiza
Uburongozi bw'umururumba
50-60% vy'iterambere mu manota ya WOMAC
40% vy'igihe gito co gutorera umuti
65% vy'ikoreshwa rya NSAID
Indwara y'umururumba w'amaraso
55-70% vy'index ya DAI mu barwayi ba UC
2-3x vyihuta gusanura umusemburo
Ihindura poroteyine zikomeye
Guhumeka Guhumeka- Imbeba
15-25% FEV1 itera imbere mu ndwara y'umusonga
Kugabanya ubushobozi bwo gukora cane
Inhibits mubit oversection
Amabwirizwa y'ikoreshwa
Dose: 300-600mg/umusi (30-40% vy’aside z’umubiri)
Ivyiza kuruta ibindi vyose: 1:1 n'ivyuma
Inzego: Ivyo vyavuyemwo bihambaye inyuma y'indwi 8-12
Ukwirinda
▲ Kwirinda mu gihe c'inda/ugurangura
▲ Ishobora gutera imiti irwanya indwara
▲ Fata imfungurwa ku barwayi b'ibisebe
Ibimenyetso vyiza
1 Ibirimwo (AKBA ni vyiza canke bingana na 5%)
② Ubuzuye- gukuraho isuzuma
③ Ubushobozi bwo gushobora kubaho
Ivyagezwe vy'abakoresha
"Inyuma y'amezi 3, imyaka cumi yanje -babara y'urusoro vyagabanutse 70%" - 45yo umukozi w'ibiro .
"Imbere y'igihe co gusubira mu nzira ya UC yagutse n'amezi 6" - 38yo IBD umurwayi
